The changes that we are witnesses are connected with overcoming the global crisis of mankind. Gro Harlem Brut land in report "Our Common Future" warns that there does not exist partial (economic, social, ecological and other) crises, but we are facing the only one – global crisis. One of its main sources is the paradigmatic difference between ecology and economics as theories. Ecology is the science based on holistic approaches and economics still resides on old mechanistic ones. Therefore it is necessary to support emerging holistic approaches in economics. First examples are human economics, green economics, new economics and ecological economics. At present we can mention that sort of new economists as Hazel Henderson, Herman Daly, Fritz Schumacher, John Cobb, Jr., Sara Parkin, Nicholas Georgescu-Roegen and many others. Shift toward holistic paradigm in economics will be the key factor to harmonize ecology and economics as sciences and to overcome the global crisis.